Amenorrhea and pituitary human chorionic gonadotrophin production in a 38-year-old presenting as pregnancy of unknown location: case report and review of literature

Background: Amenorrhea and extraplacental production of serum human chorionic gonadotropin (hCG), particularly in young women, can mimic a pregnancy unknown location. Elevated hCG the absence pose diagnostic dilemma has led to potentially harmful unwarranted interventions including chemotherapeutic agents like methotrexate or have delay necessary medical women. We report case demonstrate that amenorrhea (hCG) women Furthermore, we performed critical review literature on pituitary production. Case: A 38-year-old woman with diagnosis Silver-Russell syndrome, unicornuate uterus, history right oophorectomy for benign serous cystadenoma desire presenting provisional location.After performing thorough history, physical examination, ultrasound exams, hormone analysis [including hCG, Tumor markers, Follicle-stimulating (FSH), Luteinizing (LH), Anti-Mullerian Hormone (AMH), Estradiol (E2) levels], confirmed premature ovarian insufficiency Conclusions: In levels may increase age, are not always an indicator pregnancy. Therefore, it is imperative interpret false-positive test results rule out hCG. This will help prevent unnecessary surgical procedures treatment, chemotherapy.